Work is set to get underway on what is the first "integrated standalone" dental hospital to be constructed in the UK in over 40 years.
The seminal development, which is led by Birmingham Community Healthcare NHS Trust, will begin next month.
Partnering the trust are University of Birmingham, Birmingham and Solihull LIFT (BaS LIFT) and Calthorpe Estates.
"The new Birmingham Dental Hospital and School of Dentistry is a symbol of everything we want to achieve as a provider of high quality healthcare services," said Tracy Taylor, chief executive of Birmingham Community Healthcare NHS Trust.
"We are committed to working with our partners to provide excellent care and treatment for all the communities we serve in accessible locations, fit-for-purpose for modern healthcare provision."
The project will see the construction of a 1.23-hectare site, upon which will sit a four-storey building. This is expected to cost around £34 million.
Some of the services in the state-of-the-art building will include walk-in emergency dental care, oral medicine facilities, orthodontics and paediatric dentistry.
The current dental hospital is over half a century old and has been much in need of modernisation. Construction is expected to be finished early in 2015, with the building up and running by autumn of that year.
Ralph Minott, director of development at Calthorpe Estates said that this development is a long time coming.
He added: "Our partnership with BaSLIFT for the new Dental Hospital and School of Dentistry has been a perfect fit to that ambition, and we congratulate BaSLIFT on achieving financial close to complete their exciting proposals."
Barry Cockcroft, chief dental officer for England, described the design of the new building as innovative. He believes it will be ideal for integrating dental treatment, learning and research into one modern space.